Polar encapsidation of adenovirus DNA: cloning and DNA sequence of the left end of adenovirus type 3.

نویسندگان

  • L D Kosturko
  • S V Sharnick
  • C Tibbetts
چکیده

The left-end adenovirus type 3 DNA sequence is very similar to those of other subgroup B adenoviruses, especially in the area between the HinfI site (320 base pairs) and the early-region Ia gene. This segment of the genome has been implicated as necessary for the left-end polarity of adenovirus DNA encapsidation. This segment and the sequences flanking it are compared with the corresponding sequences of adenovirus type 5 and adenovirus type 12, and the extent and pattern of intersubgroup homologies are discussed.

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عنوان ژورنال:
  • Journal of virology

دوره 43 3  شماره 

صفحات  -

تاریخ انتشار 1982